| 英文名稱 | Rabbit MUC1 Polyclonal Antibody |
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| 應(yīng)用2 | WB |
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| 克隆類型2 | Polyclonal Antibody |
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| 別名 | ADMCKD;ADMCKD1;CA 15-3;CD227;EMA;H23AG;KL-6;MAM6;MCD;MCKD;MCKD1;MUC-1;MUC-1/SEC;MUC-1/X;MUC1/ZD;PEM;PEMT;PUM |
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| 應(yīng)用 | WB |
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| 稀釋比例 | WB1:1000-1:3000 |
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| 交叉反應(yīng) | Human Mouse |
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| 蛋白分子量 | 122kDa |
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| Gene ID | 4582 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲(chǔ)存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | Recombinant protein of human MUC1 |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | P15941 |
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| 克隆類型 | Polyclonal Antibody |
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| 來源 | Rabbit |
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| 背景資料 | This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. |
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